High throughput method to produce and screen engineered antimicrobial lanthipeptides

(University of Groningen) Nature has provided us with lots of antimicrobials. However, given the rapid increase of antimicrobial resistance, there is a need for the development of new-to-nature antibiotics. Lantibiotics are an interesting option. Molecular biologists from the University of Groningen and their colleagues in Switzerland and Germany have now developed a pipeline to create and screen large numbers of new lantibiotic peptides. The first results were published on April 1 in Nature Chemical Biology.

from EurekAlert! - Technology, Engineering and Computer Science https://ift.tt/2FS6g97